FAB1/YFR019W Literature Guide Help

Other names published for FAB1: SVL7, 1-phosphatidylinositol-3-phosphate 5-kinase, YFR019W

FAB1 - Function/Process (26)

ReferenceOther Genes Addressed
Dong XP, et al.  (2010) PI(3,5)P(2) Controls Membrane Traffic by Direct Activation of Mucolipin Ca Release Channels in the Endolysosome.LID - 38 [pii] Nat Commun 1(4)
Anand VC, et al.  (2009) Genome-wide analysis of AP-3-dependent protein transport in yeast. Mol Biol Cell 20(5):1592-604
Krick R, et al.  (2008) Piecemeal microautophagy of the nucleus requires the core macroautophagy genes. Mol Biol Cell 19(10):4492-505
Duex JE, et al.  (2006) The Vac14p-Fig4p complex acts independently of Vac7p and couples PI3,5P2 synthesis and turnover. J Cell Biol 172(5):693-704
Mollapour M, et al.  (2006) Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae. Biochem J 395(1):73-80
Phelan JP, et al.  (2006) Fab1p and AP-1 are required for trafficking of endogenously ubiquitylated cargoes to the vacuole lumen in S. cerevisiae. J Cell Sci 119(Pt 20):4225-34
Voronkova V, et al.  (2006) Snf1-dependent and Snf1-independent pathways of constitutive ADH2 expression in Saccharomyces cerevisiae. Genetics 172(4):2123-38
Lagrassa TJ and Ungermann C  (2005) The vacuolar kinase Yck3 maintains organelle fragmentation by regulating the HOPS tethering complex. J Cell Biol 168(3):401-14
Perrone GG, et al.  (2005) Genetic and environmental factors influencing glutathione homeostasis in Saccharomyces cerevisiae. Mol Biol Cell 16(1):218-30
Proszynski TJ, et al.  (2005) A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast. Proc Natl Acad Sci U S A 102(50):17981-6
Dove SK, et al.  (2004) Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J 23(9):1922-33
Katzmann DJ, et al.  (2004) Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Mol Biol Cell 15(2):468-80
Rudge SA, et al.  (2004) Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1):24-36
Shaw JD, et al.  (2003) PtdIns(3,5)P2 is required for delivery of endocytic cargo into the multivesicular body. Traffic 4(7):479-90
Bonangelino CJ, et al.  (2002) Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. J Cell Biol 156(6):1015-28
DeWald DB  (2002) Phosphoinositide signaling: vac to the future in fab1 kinase regulation. Curr Biol 12(14):R491-2
Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
Dove SK, et al.  (2002) Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body. Curr Biol 12(11):885-93
Gary JD, et al.  (2002) Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Mol Biol Cell 13(4):1238-51
McEwen RK, et al.  (1999) Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases. J Biol Chem 274(48):33905-12
Burd CG and Emr SD  (1998) Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol Cell 2(1):157-62
Cooke FT, et al.  (1998) The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae. Curr Biol 8(22):1219-22
Gary JD, et al.  (1998) Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. J Cell Biol 143(1):65-79
Odorizzi G, et al.  (1998) Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell 95(6):847-58
Zheng B, et al.  (1998) Isolation of yeast mutants defective for localization of vacuolar vital dyes. Proc Natl Acad Sci U S A 95(20):11721-6
Yamamoto A, et al.  (1995) Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast. Mol Biol Cell 6(5):525-39