APN1/YKL114C Literature Guide Help

Other names published for APN1: DNA-(apurinic or apyrimidinic site) lyase APN1, YKL114C

APN1 - Function/Process (82)

ReferenceOther Genes Addressed
Alexander MP, et al.  (2013) High levels of transcription stimulate transversions at GC base pairs in yeast. Environ Mol Mutagen 54(1):44-53
Lefevre S, et al.  (2012) Apn1 AP-endonuclease is essential for the repair of oxidatively damaged DNA bases in yeast frataxin-deficient cells. Hum Mol Genet 21(18):4060-72
Morris LP, et al.  (2012) Saccharomyces cerevisiae Apn1 mutation affecting stable protein expression mimics catalytic activity impairment: implications for assessing DNA repair capacity in humans. DNA Repair (Amst) 11(9):753-65
Kim N, et al.  (2011) The dCMP transferase activity of yeast Rev1 is biologically relevant during the bypass of endogenously generated AP sites. DNA Repair (Amst) 10(12):1262-71
Ma W, et al.  (2011) Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease. PLoS Genet 7(4):e1002059
Redrejo-Rodriguez M, et al.  (2011) New Insights in the Removal of the Hydantoins, Oxidation Product of Pyrimidines, via the Base Excision and Nucleotide Incision Repair Pathways. PLoS One 6(7):e21039
Svensson JP, et al.  (2011) Genomic phenotyping of the essential and non-essential yeast genome detects novel pathways for alkylation resistance. BMC Syst Biol 5(1):157
Acevedo-Torres K, et al.  (2009) Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage. Environ Mol Mutagen 50(4):317-27
Ho CK, et al.  (2009) Identification of nucleases and phosphatases by direct biochemical screen of the Saccharomyces cerevisiae proteome. PLoS One 4(9):e6993
Degtyareva NP, et al.  (2008) Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. Mol Cell Biol 28(17):5432-45
Ma W, et al.  (2008) Apn1 and Apn2 endonucleases prevent accumulation of repair-associated DNA breaks in budding yeast as revealed by direct chromosomal analysis. Nucleic Acids Res 36(6):1836-46
Monti P, et al.  (2008) Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. DNA Repair (Amst) 7(3):431-8
Daviet S, et al.  (2007) Major oxidative products of cytosine are substrates for the nucleotide incision repair pathway. DNA Repair (Amst) 6(1):8-18
Rusyn I, et al.  (2007) Transcriptional Networks in S. cerevisiae Linked to an Accumulation of Base Excision Repair Intermediates. PLoS ONE 2(11):e1252
Starostin KV, et al.  (2007) [Interactions of pro- and eukaryotic DNA repair enzymes with oligodeoxyribonucleotides containing clustered lesions] Mol Biol (Mosk) 41(1):112-20
Bennett SE and Kitner J  (2006) Characterization of the aldehyde reactive probe reaction with AP-sites in DNA: influence of AP-lyase on adduct stability. Nucleosides Nucleotides Nucleic Acids 25(7):823-42
Gatbonton T, et al.  (2006) Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet 2(3):e35
Phadnis N, et al.  (2006) Ntg1p, the base excision repair protein, generates mutagenic intermediates in yeast mitochondrial DNA. DNA Repair (Amst) 5(7):829-39
Auerbach P, et al.  (2005) Mutagenic specificity of endogenously generated abasic sites in Saccharomyces cerevisiae chromosomal DNA. Proc Natl Acad Sci U S A 102(49):17711-6
Daley JM and Wilson TE  (2005) Rejoining of DNA double-strand breaks as a function of overhang length. Mol Cell Biol 25(3):896-906
Fung H and Demple B  (2005) A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells. Mol Cell 17(3):463-70
Guo Y, et al.  (2005) Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage. Mol Cell Biol 25(14):5823-33
Ishchenko AA, et al.  (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90
Shatilla A, et al.  (2005) Identification of two apurinic/apyrimidinic endonucleases from Caenorhabditis elegans by cross-species complementation. DNA Repair (Amst) 4(6):655-70
Boiteux S and Guillet M  (2004) Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst) 3(1):1-12
Guzder SN, et al.  (2004) Requirement of yeast Rad1-Rad10 nuclease for the removal of 3'-blocked termini from DNA strand breaks induced by reactive oxygen species. Genes Dev 18(18):2283-91
Hanna M, et al.  (2004) Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae. DNA Repair (Amst) 3(1):51-9
Ishchenko AA, et al.  (2004) Alpha-anomeric deoxynucleotides, anoxic products of ionizing radiation, are substrates for the endonuclease IV-type AP endonucleases. Biochemistry 43(48):15210-6
Bogliolo M, et al.  (2003) Effect of S. cerevisiae APN1 protein on mammalian DNA base excision repair. Anticancer Res 23(5A):3727-34
Guillet M and Boiteux S  (2003) Origin of endogenous DNA abasic sites in Saccharomyces cerevisiae. Mol Cell Biol 23(22):8386-94