ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Function/Process (37)

Results: 1 - 30 of 37 records
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ReferenceOther Genes Addressed
Anderson JB, et al.  (2003) Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics 163(4):1287-98
Veen M, et al.  (2003) Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. FEMS Yeast Res 4(1):87-95
Edlind T, et al.  (2002) Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling. Mol Microbiol 46(1):257-68
Lamb DC, et al.  (1999) Biodiversity of the P450 catalytic cycle: yeast cytochrome b5/NADH cytochrome b5 reductase complex efficiently drives the entire sterol 14-demethylation (CYP51) reaction. FEBS Lett 462(3):283-8
Lewis DF, et al.  (1999) Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. J Enzyme Inhib 14(3):175-92
Launhardt H, et al.  (1998) Drug-induced phenotypes provide a tool for the functional analysis of yeast genes. Yeast 14(10):935-42
Venkateswarlu K, et al.  (1998) NADPH cytochrome P-450 oxidoreductase and susceptibility to ketoconazole. Antimicrob Agents Chemother 42(7):1756-61
Venkateswarlu K, et al.  (1998) The N-terminal membrane domain of yeast NADPH-cytochrome P450 (CYP) oxidoreductase is not required for catalytic activity in sterol biosynthesis or in reconstitution of CYP activity. J Biol Chem 273(8):4492-6
Venkateswarlu K, et al.  (1997) Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli. Antimicrob Agents Chemother 41(4):776-80
Barrett-Bee K and Dixon G  (1995) Ergosterol biosynthesis inhibition: a target for antifungal agents. Acta Biochim Pol 42(4):465-79
Kelly SL, et al.  (1995) Mode of action and resistance to azole antifungals associated with the formation of 14 alpha-methylergosta-8,24(28)-dien-3 beta,6 alpha-diol. Biochem Biophys Res Commun 207(3):910-5
Boscott PE and Grant GH  (1994) Modeling cytochrome P450 14 alpha demethylase (Candida albicans) from P450cam. J Mol Graph 12(3):185-92, 195
Doignon F, et al.  (1993) Resistance to imidazoles and triazoles in Saccharomyces cerevisiae as a new dominant marker. Plasmid 30(3):224-33
Kelly SL, et al.  (1993) Benzo(a)pyrene hydroxylase activity in yeast is mediated by P450 other than sterol 14 alpha-demethylase. Biochem Biophys Res Commun 197(2):428-32
Aoyama Y, et al.  (1992) Structural analysis of the interaction between the side-chain of substrates and the active site of lanosterol 14 alpha-demethylase (P-450(14)DM) of yeast. Biochim Biophys Acta 1122(3):251-5
Tuck SF, et al.  (1992) Active site topology of Saccharomyces cerevisiae lanosterol 14 alpha-demethylase (CYP51) and its G310D mutant (cytochrome P-450SG1). J Biol Chem 267(19):13175-9
Aoyama Y and Yoshida Y  (1991) Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol. Biochem Biophys Res Commun 178(3):1064-71
Aoyama Y, et al.  (1991) Role of the side chain of lanosterol in substrate recognition and catalytic activity of lanosterol 14 alpha-demethylase (cytochrome P-450 (14DM)) of yeast. Biochim Biophys Acta 1081(3):262-6
Verdiere J, et al.  (1991) CYP1 (HAP1) is a determinant effector of alternative expression of heme-dependent transcribed genes in yeast [corrected]. Mol Gen Genet 228(1-2):300-6
Wright GD, et al.  (1990) Non-sterol structural probes of the lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae. Biochim Biophys Acta 1040(1):95-101
Aoyama Y, et al.  (1989) Deformylation of 32-oxo-24,25-dihydrolanosterol by the purified cytochrome P-45014DM (lanosterol 14 alpha-demethylase) from yeast evidence confirming the intermediate step of lanosterol 14 alpha-demethylation. J Biol Chem 264(31):18502-5
Aoyama Y, et al.  (1989) Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-450(14DM) (lanosterol 14 alpha-demethylase). Biochim Biophys Acta 1001(2):196-200
Aoyama Y, et al.  (1987) Metabolism of 32-hydroxy-24,25-dihydrolanosterol by purified cytochrome P-45014DM from yeast. Evidence for contribution of the cytochrome to whole process of lanosterol 14 alpha-demethylation. J Biol Chem 262(3):1239-43
Kappeli O  (1986) Cytochromes P-450 of yeasts. Microbiol Rev 50(3):244-58
Pinto WJ, et al.  (1985) Inhibition of sterol biosynthesis by ergosterol and cholesterol in Saccharomyces cerevisiae. Biochim Biophys Acta 836(1):89-95
Aoyama Y, et al.  (1984) Yeast cytochrome P-450 catalyzing lanosterol 14 alpha-demethylation. II. Lanosterol metabolism by purified P-450(14)DM and by intact microsomes. J Biol Chem 259(3):1661-6
Bertrand JC, et al.  (1984) Influence of oxygen on the microsomal electron transport system in Saccharomyces cerevisiae. Biochimie 66(7-8):583-8
Taylor FR, et al.  (1983) Relationship between antifungal activity and inhibition of sterol biosynthesis in miconazole, clotrimazole, and 15-azasterol. Antimicrob Agents Chemother 23(4):515-21
Taylor FR, et al.  (1983) Requirement for a second sterol biosynthetic mutation for viability of a sterol C-14 demethylation defect in Saccharomyces cerevisiae. J Bacteriol 155(1):64-8
Aoyama Y, et al.  (1981) Evidence for the presence of cytochrome P-450 functional in lanosterol 14 alpha-demethylation in microsomes of aerobically grown respiring yeast. Biochim Biophys Acta 665(3):596-601
Results: 1 - 30 of 37 records
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