UBC6/YER100W Literature Guide Help

Other names published for UBC6: DOA2, E2 ubiquitin-conjugating protein UBC6, YER100W

UBC6 - Function/Process (26)

ReferenceOther Genes Addressed
Metzger MB, et al.  (2008) Degradation of a Cytosolic Protein Requires Endoplasmic Reticulum-associated Degradation Machinery. J Biol Chem 283(47):32302-16
Nakatsukasa K, et al.  (2008) Dissecting the ER-associated degradation of a misfolded polytopic membrane protein. Cell 132(1):101-12
Hiraishi H, et al.  (2006) Enhancement of Stress Tolerance in Saccharomyces cerevisiae by Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes. Biosci Biotechnol Biochem 70(11):2762-5
Liao M, et al.  (2006) Endoplasmic reticulum-associated degradation of cytochrome P450 CYP3A4 in Saccharomyces cerevisiae: further characterization of cellular participants and structural determinants. Mol Pharmacol 69(6):1897-904
Chuang SM and Madura K  (2005) Saccharomyces cerevisiae Ub-conjugating enzyme Ubc4 binds the proteasome in the presence of translationally damaged proteins. Genetics 171(4):1477-84
Wang Q and Chang A  (2003) Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family. EMBO J 22(15):3792-802
Bays NW, et al.  (2001) Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation. Nat Cell Biol 3(1):24-9
Jakob CA, et al.  (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep 2(5):423-30
Swanson R, et al.  (2001) A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation. Genes Dev 15(20):2660-74
Walter J, et al.  (2001) Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J 20(12):3124-31
Gilon T, et al.  (2000) Degradation signals recognized by the Ubc6p-Ubc7p ubiquitin-conjugating enzyme pair. Mol Cell Biol 20(19):7214-9
Lenk U and Sommer T  (2000) Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization. J Biol Chem 275(50):39403-10
Wilhovsky S, et al.  (2000) HRD gene dependence of endoplasmic reticulum-associated degradation. Mol Biol Cell 11(5):1697-708
Amshoff C, et al.  (1999) Cycloheximide, a new tool to dissect specific steps in ER-associated degradation of different substrates. Biol Chem 380(6):669-77
Plemper RK and Wolf DH  (1999) Endoplasmic reticulum degradation. Reverse protein transport and its end in the proteasome. Mol Biol Rep 26(1-2):125-30
Wang Q and Chang A  (1999) Eps1, a novel PDI-related protein involved in ER quality control in yeast. EMBO J 18(21):5972-82
Galan JM, et al.  (1998) 'ER degradation' of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway. FASEB J 12(3):315-23
Gilon T, et al.  (1998) Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae. EMBO J 17(10):2759-66
Mayer TU, et al.  (1998) Role of the proteasome in membrane extraction of a short-lived ER-transmembrane protein. EMBO J 17(12):3251-7
Sears C, et al.  (1998) NF-kappa B p105 processing via the ubiquitin-proteasome pathway. J Biol Chem 273(3):1409-19
Biederer T, et al.  (1997) Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278(5344):1806-9
Plemper RK, et al.  (1997) Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature 388(6645):891-5
Biederer T, et al.  (1996) Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J 15(9):2069-76
Hiller MM, et al.  (1996) ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway. Science 273(5282):1725-8
Chen P, et al.  (1993) Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MAT alpha 2 repressor. Cell 74(2):357-69
Sommer T and Jentsch S  (1993) A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum. Nature 365(6442):176-9