HYP2/YEL034W Literature Guide Help

Other names published for HYP2: TIF51A, eIF5A, eIF-5A, YEL034W

HYP2 - Function/Process (17)

ReferenceOther Genes Addressed
Henderson A and Hershey JW  (2011) Eukaryotic translation initiation factor (eIF) 5A stimulates protein synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 108(16):6415-9
Saini P, et al.  (2009) Hypusine-containing protein eIF5A promotes translation elongation. Nature 459(7243):118-21
Dias CA, et al.  (2008) Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis. FEBS J 275(8):1874-88
Frigieri MC, et al.  (2007) Use of a synthetic lethal screen to identify genes related to TIF51A in Saccharomyces cerevisiae. Genet Mol Res 6(1):152-65
Chatterjee I, et al.  (2006) Rapid depletion of mutant eukaryotic initiation factor 5A at restrictive temperature reveals connections to actin cytoskeleton and cell cycle progression. Mol Genet Genomics 275(3):264-76
Maag D, et al.  (2006) Communication between eukaryotic translation initiation factors 5 and 1A within the ribosomal pre-initiation complex plays a role in start site selection. J Mol Biol 356(3):724-37
Zanelli CF, et al.  (2006) eIF5A binds to translational machinery components and affects translation in yeast. Biochem Biophys Res Commun 348(4):1358-66
Zanelli CF and Valentini SR  (2005) Pkc1 acts through Zds1 and Gic1 to suppress growth and cell polarity defects of a yeast eIF5A mutant. Genetics 171(4):1571-81
Thompson GM, et al.  (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8
Valentini SR, et al.  (2002) Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling. Genetics 160(2):393-405
Kang HA and Hershey JW  (1994) Effect of initiation factor eIF-5A depletion on protein synthesis and proliferation of Saccharomyces cerevisiae. J Biol Chem 269(6):3934-40
Kang HA, et al.  (1993) Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine in Saccharomyces cerevisiae. J Biol Chem 268(20):14750-6
Schwelberger HG, et al.  (1993) Translation initiation factor eIF-5A expressed from either of two yeast genes or from human cDNA. Functional identity under aerobic and anaerobic conditions. J Biol Chem 268(19):14018-25
Klier H and Lottspeich F  (1992) Detection of the hypusine-containing protein (HP = eIF-5A) in crude yeast extracts by two-dimensional western blots. Electrophoresis 13(9-10):732-5
Wohl T, et al.  (1992) Chromosomal localization of the HYP2-gene in Saccharomyces cerevisiae and use of pulsed-field gel electrophoresis for detection of irregular recombination events in gene disruption experiments. Electrophoresis 13(9-10):651-3
Schnier J, et al.  (1991) Translation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Mol Cell Biol 11(6):3105-14
Hershey JW, et al.  (1990) The role of mammalian initiation factor eIF-4D and its hypusine modification in translation. Biochim Biophys Acta 1050(1-3):160-2