TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Disease Gene Related (8)

ReferenceOther Genes Addressed
Baxter J and Diffley JF  (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Mol Cell 30(6):790-802
Malik M, et al.  (2006) Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage. Mol Cancer Ther 5(6):1405-14
Hellauer K, et al.  (2005) Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae. Mol Pharmacol 68(5):1365-75
Jiang X  (2005) Random mutagenesis of the B'A' core domain of yeast DNA topoisomerase II and large-scale screens of mutants resistant to the anticancer drug etoposide. Biochem Biophys Res Commun 327(2):597-603
Lu HR, et al.  (2005) Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase. Mol Pharmacol 68(4):983-94
Suda N, et al.  (2004) The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity. Nucleic Acids Res 32(5):1767-73
Sabourin M, et al.  (2003) Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks. Nucleic Acids Res 31(15):4373-84
Vessey CJ, et al.  (1999) Genetic disorders associated with cancer predisposition and genomic instability. Prog Nucleic Acid Res Mol Biol 63():189-221