NDI1/YML120C Literature Guide Help

Other names published for NDI1: NADH-ubiquinone reductase (H(+)-translocating) NDI1, YML120C

NDI1 - Disease Gene Related (14)

ReferenceOther Genes Addressed
Chadderton N, et al.  (2013) Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy. Eur J Hum Genet 21(1):62-8
Feng Y, et al.  (2012) Structural insight into the type-II mitochondrial NADH dehydrogenases. Nature 491(7424):478-82
Vilain S, et al.  (2012) The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants. PLoS Genet 8(1):e1002456
Marella M, et al.  (2011) No immune responses by the expression of the yeast ndi1 protein in rats. PLoS One 6(10):e25910
Barber-Singh J, et al.  (2010) Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model. Parkinsons Dis 2011():438370
Marella M, et al.  (2010) Successful Amelioration of Mitochondrial Optic Neuropathy Using the Yeast NDI1 Gene in a Rat Animal Model. PLoS One 5(7):e11472
Decorby A, et al.  (2007) Expression of Ndi1p, an alternative NADH:ubiquinone oxidoreductase, increases mitochondrial membrane potential in a C. elegans model of mitochondrial disease. Biochim Biophys Acta 1767(9):1157-63
Sherer TB, et al.  (2007) Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. J Neurochem 100(6):1469-79
Seo BB, et al.  (2006) In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease. J Biol Chem 281(20):14250-5
Yagi T, et al.  (2006) Can a single subunit yeast NADH dehydrogenase (Ndi1) remedy diseases caused by respiratory complex I defects? Rejuvenation Res 9(2):191-7
Seo BB, et al.  (2004) Functional expression of the single subunit NADH dehydrogenase in mitochondria in vivo: a potential therapy for complex I deficiencies. Hum Gene Ther 15(9):887-95
Seo BB, et al.  (2002) A single-subunit NADH-quinone oxidoreductase renders resistance to mammalian nerve cells against complex I inhibition. Mol Ther 6(3):336-41
Bai Y, et al.  (2001) Lack of complex I activity in human cells carrying a mutation in MtDNA-encoded ND4 subunit is corrected by the Saccharomyces cerevisiae NADH-quinone oxidoreductase (NDI1) gene. J Biol Chem 276(42):38808-13
Seo BB, et al.  (2000) Use of the NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae as a possible cure for complex I defects in human cells. J Biol Chem 275(48):37774-8