SIR2/YDL042C Literature Guide Help

Other names published for SIR2: MAR1, YDL042C

SIR2 - Disease Gene Related (13)

ReferenceOther Genes Addressed
Sampaio-Marques B, et al.  (2012) SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 8(10):1494-509
Alba Sorolla M, et al.  (2011) Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation. Arch Biochem Biophys 510(1):27-34
Schug TT and Li X  (2011) Sirtuin 1 in lipid metabolism and obesity. Ann Med 43(3):198-211
Yamamoto T and Sadoshima J  (2011) Protection of the heart against ischemia/reperfusion by silent information regulator 1. Trends Cardiovasc Med 21(1):27-32
Balcerczyk A and Pirola L  (2010) Therapeutic potential of activators and inhibitors of sirtuins. Biofactors 36(5):383-93
Duan W and Ross CA  (2010) Potential therapeutic targets for neurodegenerative diseases: lessons learned from calorie restriction. Curr Drug Targets 11(10):1281-92
Ottaviani A, et al.  (2008) Telomeric position effect: From the yeast paradigm to human pathologies? Biochimie 90(1):93-107
Sedivy JM, et al.  (2008) Aging by epigenetics--a consequence of chromatin damage? Exp Cell Res 314(9):1909-17
Hida Y, et al.  (2007) Strong expression of a longevity-related protein, SIRT1, in Bowen's disease. Arch Dermatol Res 299(2):103-6
Trapp J and Jung M  (2006) The role of NAD+ dependent histone deacetylases (sirtuins) in ageing. Curr Drug Targets 7(11):1553-60
Guarente L  (2005) Calorie restriction and SIR2 genes--towards a mechanism. Mech Ageing Dev 126(9):923-8
Olaharski AJ, et al.  (2005) The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases. PLoS Genet 1(6):e77
Smith J  (2002) Human Sir2 and the 'silencing' of p53 activity. Trends Cell Biol 12(9):404-6