TOP2/YNL088W Literature Guide Help

Other names published for TOP2: TOR3, TRF3, DNA topoisomerase 2, YNL088W

TOP2 - Cross-species Expression (13)

ReferenceOther Genes Addressed
Joshi RS, et al.  (2012) Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res 40(16):7907-15
D'Ambrosio C, et al.  (2008) Condensin-Dependent rDNA Decatenation Introduces a Temporal Pattern to Chromosome Segregation. Curr Biol 18(14):1084-9
Meczes EL, et al.  (2008) The impact of the human DNA topoisomerase II C-terminal domain on activity. PLoS ONE 3(3):e1754
Mouchel NA and Jenkins JR  (2006) The identification of a functional interaction between PKC and topoisomerase II. FEBS Lett 580(1):51-7
Suda N, et al.  (2004) The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity. Nucleic Acids Res 32(5):1767-73
Sengupta T, et al.  (2003) Functional dissection of the C-terminal domain of type II DNA topoisomerase from the kinetoplastid hemoflagellate Leishmania donovani. Nucleic Acids Res 31(18):5305-16
Singh BN, et al.  (2003) Molecular characterization of a nuclear topoisomerase II from Nicotiana tabacum that functionally complements a temperature-sensitive topoisomerase II yeast mutant. Plant Mol Biol 52(5):1063-76
Suda N, et al.  (2003) Function of the loop residue Thr792 in human DNA topoisomerase II alpha. Biochem Biophys Res Commun 303(1):46-51
Vilain N, et al.  (2003) Modulation of drug sensitivity in yeast cells by the ATP-binding domain of human DNA topoisomerase IIalpha. Nucleic Acids Res 31(19):5714-22
Jensen LH, et al.  (2000) A novel mechanism of cell killing by anti-topoisomerase II bisdioxopiperazines. J Biol Chem 275(3):2137-46
Wessel I, et al.  (1999) Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform. Cancer Res 59(14):3442-50
Wasserman RA, et al.  (1993) Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast. Cancer Res 53(15):3591-6
Adachi N, et al.  (1992) Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation. Nucleic Acids Res 20(20):5297-303