NDI1/YML120C Literature Guide Help

Other names published for NDI1: NADH-ubiquinone reductase (H(+)-translocating) NDI1, YML120C

NDI1 - Cross-species Expression (27)

ReferenceOther Genes Addressed
Chadderton N, et al.  (2013) Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy. Eur J Hum Genet 21(1):62-8
Vilain S, et al.  (2012) The Yeast Complex I Equivalent NADH Dehydrogenase Rescues pink1 Mutants. PLoS Genet 8(1):e1002456
Marella M, et al.  (2011) No immune responses by the expression of the yeast ndi1 protein in rats. PLoS One 6(10):e25910
Perry CN, et al.  (2011) Xenotransplantation of mitochondrial electron transfer enzyme, ndi1, in myocardial reperfusion injury. PLoS One 6(2):e16288
Sharma LK, et al.  (2011) Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activation. Hum Mol Genet 20(23):4605-16
Bahadorani S, et al.  (2010) Neuronal expression of a single-subunit yeast NADH-ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan. Aging Cell 9(2):191-202
Barber-Singh J, et al.  (2010) Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model. Parkinsons Dis 2011():438370
Marella M, et al.  (2010) Successful Amelioration of Mitochondrial Optic Neuropathy Using the Yeast NDI1 Gene in a Rat Animal Model. PLoS One 5(7):e11472
Sanz A, et al.  (2010) Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction. Proc Natl Acad Sci U S A 107(20):9105-10
Barber-Singh J, et al.  (2009) Neuroprotective Effect of Long-term NDI1 Gene Expression in a Chronic Mouse Model of Parkinson Disorder. Rejuvenation Res 12(4):259-67
Ota S, et al.  (2009) Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism. Biochem Biophys Res Commun 388(2):311-6
Perales-Clemente E, et al.  (2008) Restoration of electron transport without proton pumping in mammalian mitochondria. Proc Natl Acad Sci U S A 105(48):18735-9
Decorby A, et al.  (2007) Expression of Ndi1p, an alternative NADH:ubiquinone oxidoreductase, increases mitochondrial membrane potential in a C. elegans model of mitochondrial disease. Biochim Biophys Acta 1767(9):1157-63
Escobar-Khondiker M, et al.  (2007) Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons. J Neurosci 27(29):7827-37
Marella M, et al.  (2007) Mechanism of cell death caused by complex I defects in a rat dopaminergic cell line. J Biol Chem 282(33):24146-56
Park JS, et al.  (2007) Yeast NDI1 improves oxidative phosphorylation capacity and increases protection against oxidative stress and cell death in cells carrying a Leber's hereditary optic neuropathy mutation. Biochim Biophys Acta 1772(5):533-42
Sherer TB, et al.  (2007) Mechanism of toxicity of pesticides acting at complex I: relevance to environmental etiologies of Parkinson's disease. J Neurochem 100(6):1469-79
Seo BB, et al.  (2006) In vivo complementation of complex I by the yeast Ndi1 enzyme. Possible application for treatment of Parkinson disease. J Biol Chem 281(20):14250-5
Seo BB, et al.  (2006) The single subunit NADH dehydrogenase reduces generation of reactive oxygen species from complex I. FEBS Lett 580(26):6105-8
Yagi T, et al.  (2006) Can a single subunit yeast NADH dehydrogenase (Ndi1) remedy diseases caused by respiratory complex I defects? Rejuvenation Res 9(2):191-7
Tarrio N, et al.  (2005) The nuclear genes encoding the internal (KlNDI1) and external (KlNDE1) alternative NAD(P)H:ubiquinone oxidoreductases of mitochondria from Kluyveromyces lactis. Biochim Biophys Acta 1707(2-3):199-210
Bai Y, et al.  (2004) Genetic and functional analysis of mitochondrial DNA-encoded complex I genes. Ann N Y Acad Sci 1011:272-83
Seo BB, et al.  (2004) Functional expression of the single subunit NADH dehydrogenase in mitochondria in vivo: a potential therapy for complex I deficiencies. Hum Gene Ther 15(9):887-95
Sherer TB, et al.  (2003) Mechanism of toxicity in rotenone models of Parkinson's disease. J Neurosci 23(34):10756-64
Seo BB, et al.  (2002) A single-subunit NADH-quinone oxidoreductase renders resistance to mammalian nerve cells against complex I inhibition. Mol Ther 6(3):336-41
Seo BB, et al.  (1999) Modulation of oxidative phosphorylation of human kidney 293 cells by transfection with the internal rotenone-insensitive NADH-quinone oxidoreductase (NDI1) gene of Saccharomyces cerevisiae. Biochim Biophys Acta 1412(1):56-65
Seo BB, et al.  (1998) Molecular remedy of complex I defects: rotenone-insensitive internal NADH-quinone oxidoreductase of Saccharomyces cerevisiae mitochondria restores the NADH oxidase activity of complex I-deficient mammalian cells. Proc Natl Acad Sci U S A 95(16):9167-71