HSP82/YPL240C Literature Guide Help

Other names published for HSP82: HSP90, Hsp90 family chaperone HSP82, YPL240C

HSP82 - Cross-species Expression (12)

ReferenceOther Genes Addressed
Millson SH, et al.  (2010) A simple yeast-based system for analyzing inhibitor resistance in the human cancer drug targets Hsp90alpha/beta. Biochem Pharmacol 79(11):1581-8
Song H, et al.  (2010) Expression of five AtHsp90 genes in Saccharomyces cerevisiae reveals functional differences of AtHsp90s under abiotic stresses. J Plant Physiol 167(14):1172-1178
Xu X, et al.  (2010) Functional characterization of AtHsp90.3 in Saccharomyces cerevisiae and Arabidopsis thaliana under heat stress. Biotechnol Lett 32(7):979-87
Prodromou C, et al.  (2009) Structural basis of the radicicol resistance displayed by a fungal hsp90. ACS Chem Biol 4(4):289-97
Tsutsumi S, et al.  (2009) Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. Nat Struct Mol Biol 16(11):1141-7
Wider D, et al.  (2009) The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities. Mol Biochem Parasitol 164(2):147-52
Millson SH, et al.  (2007) Expressed as the sole Hsp90 of yeast, the alpha and beta isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90beta generates sensitivity to the Hsp90 inhibitor radicicol. FEBS J 274(17):4453-63
Park H, et al.  (2007) A novel class of Hsp90 inhibitors isolated by structure-based virtual screening. Bioorg Med Chem Lett 17(22):6345-9
MacLean MJ, et al.  (2005) A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90alpha. Biochem Biophys Res Commun 337(1):133-7
Piper PW, et al.  (2003) Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene 302(1-2):165-70
Palmer G, et al.  (1995) Trypanosoma cruzi heat-shock protein 90 can functionally complement yeast. Mol Biochem Parasitol 70(1-2):199-202
Minami Y, et al.  (1994) The carboxy-terminal region of mammalian HSP90 is required for its dimerization and function in vivo. Mol Cell Biol 14(2):1459-64