ERG11/YHR007C Literature Guide Help

Other names published for ERG11: CYP51, sterol 14-demethylase, YHR007C

ERG11 - Cross-species Expression (17)

ReferenceOther Genes Addressed
Fiori A and Van Dijck P  (2012) Potent synergistic effect of doxycycline with fluconazole against Candida albicans is mediated by interference with iron homeostasis. Antimicrob Agents Chemother 56(7):3785-96
Hull CM, et al.  (2012) Facultative sterol uptake in an ergosterol-deficient clinical isolate of Candida glabrata harboring a missense mutation in ERG11 and exhibiting cross-resistance to azoles and amphotericin B. Antimicrob Agents Chemother 56(8):4223-32
Alcazar-Fuoli L, et al.  (2011) Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae. Med Mycol 49(3):276-84
Alcazar-Fuoli L, et al.  (2011) Three-dimensional models of 14a-sterol demethylase (Cyp51A) from Aspergillus lentulus and Aspergillus fumigatus: an insight into differences in voriconazole interaction. Int J Antimicrob Agents 38(5):426-34
Nkinin SW, et al.  (2011) Pneumocystis carinii sterol 14a-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. J Eukaryot Microbiol 58(4):383-92
Martel CM, et al.  (2010) Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (Sterol 14{alpha}-Demethylase) Doxycycline-Regulated Mutant and Screening of the Azole Sensitivity of Aspergillus fumigatus Isoenzymes CYP51A and CYP51B. Antimicrob Agents Chemother 54(11):4920-3
Lamping E, et al.  (2009) Abc1p Is a Multidrug Efflux Transporter That Tips the Balance in Favor of Innate Azole Resistance in Candida krusei. Antimicrob Agents Chemother 53(2):354-369
Parker JE, et al.  (2008) Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. Antimicrob Agents Chemother 52(10):3597-603
Chen SH, et al.  (2007) Identification of Y118 Amino Acid Residue in Candida albicans Sterol 14alpha-Demethylase Associated with the Enzyme Activity and Selective Antifungal Activity of Azole Analogues. Biol Pharm Bull 30(7):1246-53
Chau AS, et al.  (2006) Molecular Basis for Enhanced Activity of Posaconazole against Absidia corymbifera and Rhizopus oryzae. Antimicrob Agents Chemother 50(11):3917-9
Revankar SG, et al.  (2004) Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. Biochem Biophys Res Commun 324(2):719-28
Buckner FS, et al.  (2003) Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. Mol Biochem Parasitol 132(2):75-81
Morales IJ, et al.  (2003) Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. Am J Respir Cell Mol Biol 29(2):232-8
Favre B, et al.  (1999) Multiple amino acid substitutions in lanosterol 14alpha-demethylase contribute to azole resistance in Candida albicans. Microbiology 145 ( Pt 10)():2715-25
Lamb DC, et al.  (1999) Characteristics of the heterologously expressed human lanosterol 14alpha-demethylase (other names: P45014DM, CYP51, P45051) and inhibition of the purified human and Candida albicans CYP51 with azole antifungal agents. Yeast 15(9):755-63
Sanglard D, et al.  (1998) Amino acid substitutions in the cytochrome P-450 lanosterol 14alpha-demethylase (CYP51A1) from azole-resistant Candida albicans clinical isolates contribute to resistance to azole antifungal agents. Antimicrob Agents Chemother 42(2):241-53
Kirsch DR, et al.  (1988) Isolation of the gene for cytochrome P450L1A1 (lanosterol 14 alpha-demethylase) from Candida albicans. Gene 68(2):229-37