MEC1/YBR136W Literature Guide Help

Other names published for MEC1: ESR1, SAD3, RAD31, YBR136W

MEC1 - Cellular Location (21)

ReferenceOther Genes Addressed
Hector RE, et al.  (2012) Mec1p associates with functionally compromised telomeres. Chromosoma 121(3):277-90
Kubota T, et al.  (2011) Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint. Mol Cell Proteomics 10(7):M110.005561
McGee JS, et al.  (2010) Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair. Nat Struct Mol Biol 17(12):1438-45
Vidanes GM, et al.  (2010) CDC5 Inhibits the Hyperphosphorylation of the Checkpoint Kinase Rad53, Leading to Checkpoint Adaptation. PLoS Biol 8(1):e1000286
Nagai S, et al.  (2008) Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science 322(5901):597-602
Dubrana K, et al.  (2007) The processing of double-strand breaks and binding of single-strand-binding proteins RPA and Rad51 modulate the formation of ATR-kinase foci in yeast. J Cell Sci 120(Pt 23):4209-20
Hirano Y and Sugimoto K  (2007) Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends. Mol Biol Cell 18(6):2026-36
Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
Garber PM, et al.  (2005) Damage in transition. Trends Biochem Sci 30(2):63-6
Nakada D, et al.  (2004) Requirement of the Mre11 complex and exonuclease 1 for activation of the Mec1 signaling pathway. Mol Cell Biol 24(22):10016-25
Shroff R, et al.  (2004) Distribution and dynamics of chromatin modification induced by a defined DNA double-strand break. Curr Biol 14(19):1703-11
Takata H, et al.  (2004) Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo. Mol Cell 14(4):515-22
Chan SW and Blackburn EH  (2003) Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining. Mol Cell 11(5):1379-87
Cobb JA, et al.  (2003) DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. EMBO J 22(16):4325-36
Osborn AJ and Elledge SJ  (2003) Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Genes Dev 17(14):1755-67
Pasero P, et al.  (2003) Multiple roles of replication forks in S phase checkpoints: sensors, effectors and targets. Cell Cycle 2(6):568-72
Sickmann A, et al.  (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12
Rouse J and Jackson SP  (2002) Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo. Mol Cell 9(4):857-69
Shimada K, et al.  (2002) ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase. Genes Dev 16(24):3236-52
Hu F, et al.  (2001) Asf1 links Rad53 to control of chromatin assembly. Genes Dev 15(9):1061-6
Mallory JC and Petes TD  (2000) Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc Natl Acad Sci U S A 97(25):13749-54