Search results for Literature Guide pages at SGD
Your query, YPK1, returned 3 hits to the following gene names:
| Match | Gene Name | Systematic Name | Alias(es) | Position Info | Description |
|---|---|---|---|---|---|
| YPK1 | MCK1 | YNL307C | YPK1, CMS1 | Dual-specificity ser/thr and tyrosine protein kinase; roles in chromosome segregation, meiotic entry, genome stability, phosphorylation-dependent protein degradation (Rcn1p and Cdc6p), inhibition of protein kinase A, transcriptional regulation, inhibition of RNA pol III, calcium stress and inhibition of Clb2p-Cdc28p after nuclear division; MCK1 has a paralog, YGK3, that arose from the whole genome duplication | |
| YPK1 | TOK1 | YJL093C | DUK1, YKC1, YORK, YPK1 | Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin | |
| YPK1 | YPK1 | YKL126W | SLI2 | Serine/threonine protein kinase; phosphorylates and downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p (inhibitors of serine:palmitoyl-coenzyme A transferase) by phosphorylation in response to compromised sphingolipid synthesis; mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; homolog of mammalian kinase SGK; YPK1 has a paralog, YPK2, that arose from the whole genome duplication |
