YAR052C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 7 5.6%
Arg[R] 0 0.0%
Asn[N] 0 0.0%
Asp[D] 5 4.0%
Cys[C] 5 4.0%
Gln[Q] 2 1.6%
Glu[E] 11 8.7%
Gly[G] 5 4.0%
His[H] 7 5.6%
Ile[I] 5 4.0%
Leu[L] 6 4.8%
Lys[K] 0 0.0%
Met[M] 3 2.4%
Phe[F] 2 1.6%
Pro[P] 4 3.2%
Ser[S] 12 9.5%
Thr[T] 13 10.3%
Trp[W] 0 0.0%
Tyr[Y] 2 1.6%
Val[V] 37 29.4%
Total Length 126

Instability index
Instability index (II) 21.51
This classifies the protein as stable

Atomic composition
Carbon 583
Hydrogen 940
Nitrogen 142
Oxygen 188
Sulfur 8
Total number of atoms 1861
Formula = C583H940N142O188S8

Estimated half-life
mammalian reticulocytes (in vitro) 30 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 3230
assuming NO Cys residues appear as half cystines 2980

Aliphatic index
Aliphatic index 124.76

Coding Region Translation Calculations
Codon Bias -0.092
Codon Adaptation Index 0.076
Frequency of Optimal Codons 0.390
Hydropathicity of Protein 0.968
Aromaticity Score 0.032