YAR043C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 7 6.7%
Arg[R] 4 3.8%
Asn[N] 2 1.9%
Asp[D] 9 8.6%
Cys[C] 4 3.8%
Gln[Q] 4 3.8%
Glu[E] 8 7.6%
Gly[G] 10 9.5%
His[H] 7 6.7%
Ile[I] 2 1.9%
Leu[L] 10 9.5%
Lys[K] 1 1.0%
Met[M] 0 0.0%
Phe[F] 7 6.7%
Pro[P] 1 1.0%
Ser[S] 5 4.8%
Thr[T] 2 1.9%
Trp[W] 1 1.0%
Tyr[Y] 1 1.0%
Val[V] 20 19.0%
Total Length 105

Instability index
Instability index (II) 28.06
This classifies the protein as stable

Atomic composition
Carbon 512
Hydrogen 781
Nitrogen 139
Oxygen 154
Sulfur 4
Total number of atoms 1590
Formula = C512H781N139O154S4

Estimated half-life
mammalian reticulocytes (in vitro) 3.5 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 7240
assuming NO Cys residues appear as half cystines 6990

Aliphatic index
Aliphatic index 106.48

Coding Region Translation Calculations
Codon Bias 0.059
Codon Adaptation Index 0.114
Frequency of Optimal Codons 0.442
Hydropathicity of Protein 0.335
Aromaticity Score 0.086