YKL023C-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 3 4.0%
Arg[R] 4 5.3%
Asn[N] 7 9.3%
Asp[D] 0 0.0%
Cys[C] 0 0.0%
Gln[Q] 2 2.7%
Glu[E] 3 4.0%
Gly[G] 3 4.0%
His[H] 2 2.7%
Ile[I] 2 2.7%
Leu[L] 7 9.3%
Lys[K] 9 12.0%
Met[M] 1 1.3%
Phe[F] 4 5.3%
Pro[P] 5 6.7%
Ser[S] 7 9.3%
Thr[T] 5 6.7%
Trp[W] 0 0.0%
Tyr[Y] 3 4.0%
Val[V] 8 10.7%
Total Length 75

Instability index
Instability index (II) 35.45
This classifies the protein as stable

Atomic composition
Carbon 386
Hydrogen 623
Nitrogen 109
Oxygen 106
Sulfur 1
Total number of atoms 1225
Formula = C386H623N109O106S1

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 4470 M-1 cm-1

Aliphatic index
Aliphatic index 81.73

Coding Region Translation Calculations
Codon Bias 0.073
Codon Adaptation Index 0.099
Frequency of Optimal Codons 0.446
Hydropathicity of Protein -0.480
Aromaticity Score 0.093