YER107W-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 8 7.5%
Arg[R] 3 2.8%
Asn[N] 2 1.9%
Asp[D] 4 3.8%
Cys[C] 4 3.8%
Gln[Q] 2 1.9%
Glu[E] 3 2.8%
Gly[G] 6 5.7%
His[H] 1 0.9%
Ile[I] 9 8.5%
Leu[L] 9 8.5%
Lys[K] 7 6.6%
Met[M] 5 4.7%
Phe[F] 8 7.5%
Pro[P] 3 2.8%
Ser[S] 15 14.2%
Thr[T] 1 0.9%
Trp[W] 1 0.9%
Tyr[Y] 4 3.8%
Val[V] 11 10.4%
Total Length 106

Instability index
Instability index (II) 30.26
This classifies the protein as stable

Atomic composition
Carbon 534
Hydrogen 839
Nitrogen 129
Oxygen 145
Sulfur 9
Total number of atoms 1656
Formula = C534H839N129O145S9

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 11710 M-1 cm-1
assuming NO Cys residues appear as half cystines 11460 M-1 cm-1
assuming all Cys residues are reduced 11460 M-1 cm-1
assuming all pairs of Cys residues form cystines 11710 M-1 cm-1

Aliphatic index
Aliphatic index 103.87

Coding Region Translation Calculations
Codon Bias -0.030
Codon Adaptation Index 0.108
Frequency of Optimal Codons 0.390
Hydropathicity of Protein 0.648
Aromaticity Score 0.123