YKL156C-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 3 7.9%
Arg[R] 1 2.6%
Asn[N] 3 7.9%
Asp[D] 1 2.6%
Cys[C] 2 5.3%
Gln[Q] 1 2.6%
Glu[E] 1 2.6%
Gly[G] 3 7.9%
His[H] 1 2.6%
Ile[I] 0 0.0%
Leu[L] 4 10.5%
Lys[K] 3 7.9%
Met[M] 1 2.6%
Phe[F] 3 7.9%
Pro[P] 2 5.3%
Ser[S] 3 7.9%
Thr[T] 2 5.3%
Trp[W] 1 2.6%
Tyr[Y] 1 2.6%
Val[V] 2 5.3%
Total Length 38

Instability index
Instability index (II) 28.78
This classifies the protein as stable

Atomic composition
Carbon 190
Hydrogen 289
Nitrogen 51
Oxygen 53
Sulfur 3
Total number of atoms 586
Formula = C190H289N51O53S3

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 7115 M-1 cm-1
assuming NO Cys residues appear as half cystines 6990 M-1 cm-1
assuming all Cys residues are reduced 6990 M-1 cm-1
assuming all pairs of Cys residues form cystines 7115 M-1 cm-1

Aliphatic index
Aliphatic index 64.21

Coding Region Translation Calculations
Codon Bias 0.008
Codon Adaptation Index 0.117
Frequency of Optimal Codons 0.389
Hydropathicity of Protein -0.171
Aromaticity Score 0.132