YMR230W-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 0 0.0%
Arg[R] 5 8.1%
Asn[N] 5 8.1%
Asp[D] 1 1.6%
Cys[C] 8 12.9%
Gln[Q] 2 3.2%
Glu[E] 0 0.0%
Gly[G] 1 1.6%
His[H] 3 4.8%
Ile[I] 7 11.3%
Leu[L] 5 8.1%
Lys[K] 1 1.6%
Met[M] 3 4.8%
Phe[F] 6 9.7%
Pro[P] 0 0.0%
Ser[S] 6 9.7%
Thr[T] 0 0.0%
Trp[W] 0 0.0%
Tyr[Y] 1 1.6%
Val[V] 8 12.9%
Total Length 62

Instability index
Instability index (II) 39.61
This classifies the protein as stable

Atomic composition
Carbon 322
Hydrogen 513
Nitrogen 91
Oxygen 79
Sulfur 11
Total number of atoms 1016
Formula = C322H513N91O79S11

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 1990 M-1 cm-1
assuming NO Cys residues appear as half cystines 1490 M-1 cm-1
assuming all Cys residues are reduced 1490 M-1 cm-1
assuming all pairs of Cys residues form cystines 1990 M-1 cm-1

Aliphatic index
Aliphatic index 112.90

Coding Region Translation Calculations
Codon Bias 0.058
Codon Adaptation Index 0.158
Frequency of Optimal Codons 0.475
Hydropathicity of Protein 0.905
Aromaticity Score 0.113