YDR169C-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 2 4.1%
Arg[R] 7 14.3%
Asn[N] 2 4.1%
Asp[D] 0 0.0%
Cys[C] 1 2.0%
Gln[Q] 3 6.1%
Glu[E] 1 2.0%
Gly[G] 3 6.1%
His[H] 1 2.0%
Ile[I] 1 2.0%
Leu[L] 5 10.2%
Lys[K] 3 6.1%
Met[M] 5 10.2%
Phe[F] 2 4.1%
Pro[P] 1 2.0%
Ser[S] 10 20.4%
Thr[T] 1 2.0%
Trp[W] 0 0.0%
Tyr[Y] 0 0.0%
Val[V] 1 2.0%
Total Length 49

Instability index
Instability index (II) 72.84
This classifies the protein as unstable

Atomic composition
Carbon 232
Hydrogen 398
Nitrogen 80
Oxygen 68
Sulfur 6
Total number of atoms 784
Formula = C232H398N80O68S6

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 0 M-1 cm-1
assuming NO Cys residues appear as half cystines 0 M-1 cm-1
assuming all Cys residues are reduced 0 M-1 cm-1
assuming all pairs of Cys residues form cystines 0 M-1 cm-1

Aliphatic index
Aliphatic index 57.76

Coding Region Translation Calculations
Codon Bias 0.310
Codon Adaptation Index 0.164
Frequency of Optimal Codons 0.545
Hydropathicity of Protein -0.612
Aromaticity Score 0.041