MOS1/YCL057C-A Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 7 7.2%
Arg[R] 5 5.2%
Asn[N] 3 3.1%
Asp[D] 4 4.1%
Cys[C] 0 0.0%
Gln[Q] 4 4.1%
Glu[E] 2 2.1%
Gly[G] 11 11.3%
His[H] 0 0.0%
Ile[I] 4 4.1%
Leu[L] 6 6.2%
Lys[K] 7 7.2%
Met[M] 3 3.1%
Phe[F] 7 7.2%
Pro[P] 3 3.1%
Ser[S] 13 13.4%
Thr[T] 6 6.2%
Trp[W] 2 2.1%
Tyr[Y] 1 1.0%
Val[V] 9 9.3%
Total Length 97

Instability index
Instability index (II) 54.86
This classifies the protein as unstable

Atomic composition
Carbon 465
Hydrogen 736
Nitrogen 128
Oxygen 137
Sulfur 3
Total number of atoms 1469
Formula = C465H736N128O137S3

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 12490 M-1 cm-1

Aliphatic index
Aliphatic index 74.33

Coding Region Translation Calculations
Codon Bias 0.202
Codon Adaptation Index 0.149
Frequency of Optimal Codons 0.511
Hydropathicity of Protein -0.059
Aromaticity Score 0.103