YDR098C-B Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 82 4.7%
Arg[R] 71 4.0%
Asn[N] 129 7.4%
Asp[D] 102 5.8%
Cys[C] 13 0.7%
Gln[Q] 74 4.2%
Glu[E] 87 5.0%
Gly[G] 69 3.9%
His[H] 62 3.5%
Ile[I] 128 7.3%
Leu[L] 139 7.9%
Lys[K] 129 7.4%
Met[M] 31 1.8%
Phe[F] 53 3.0%
Pro[P] 114 6.5%
Ser[S] 176 10.0%
Thr[T] 134 7.6%
Trp[W] 14 0.8%
Tyr[Y] 76 4.3%
Val[V] 72 4.1%
Total Length 1755

Instability index
Instability index (II) 47.75
This classifies the protein as unstable

Atomic composition
Carbon 8790
Hydrogen 13784
Nitrogen 2438
Oxygen 2723
Sulfur 44
Total number of atoms 27779
Formula = C8790H13784N2438O2723S44

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 190990 M-1 cm-1
assuming NO Cys residues appear as half cystines 190240 M-1 cm-1
assuming all Cys residues are reduced 190240 M-1 cm-1
assuming all pairs of Cys residues form cystines 190990 M-1 cm-1

Aliphatic index
Aliphatic index 75.90

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000