ATP15/YPL271W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 11 17.7%
Arg[R] 3 4.8%
Asn[N] 3 4.8%
Asp[D] 1 1.6%
Cys[C] 0 0.0%
Gln[Q] 4 6.5%
Glu[E] 2 3.2%
Gly[G] 2 3.2%
His[H] 0 0.0%
Ile[I] 3 4.8%
Leu[L] 4 6.5%
Lys[K] 4 6.5%
Met[M] 1 1.6%
Phe[F] 1 1.6%
Pro[P] 2 3.2%
Ser[S] 7 11.3%
Thr[T] 7 11.3%
Trp[W] 1 1.6%
Tyr[Y] 4 6.5%
Val[V] 2 3.2%
Total Length 62

Instability index
Instability index (II) 50.63
This classifies the protein as unstable

Atomic composition
Carbon 297
Hydrogen 473
Nitrogen 83
Oxygen 94
Sulfur 1
Total number of atoms 948
Formula = C297H473N83O94S1

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 11460 M-1 cm-1

Aliphatic index
Aliphatic index 71.13

Coding Region Translation Calculations
Codon Bias 0.129
Codon Adaptation Index 0.168
Frequency of Optimal Codons 0.467
Hydropathicity of Protein -0.373
Aromaticity Score 0.097