PDR5/YOR153W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 120 7.9%
Arg[R] 68 4.5%
Asn[N] 70 4.6%
Asp[D] 66 4.4%
Cys[C] 28 1.9%
Gln[Q] 56 3.7%
Glu[E] 84 5.6%
Gly[G] 94 6.2%
His[H] 25 1.7%
Ile[I] 88 5.8%
Leu[L] 134 8.9%
Lys[K] 87 5.8%
Met[M] 42 2.8%
Phe[F] 90 6.0%
Pro[P] 59 3.9%
Ser[S] 126 8.3%
Thr[T] 81 5.4%
Trp[W] 23 1.5%
Tyr[Y] 77 5.1%
Val[V] 93 6.2%
Total Length 1511

Instability index
Instability index (II) 35.95
This classifies the protein as stable

Atomic composition
Carbon 7716
Hydrogen 11845
Nitrogen 2001
Oxygen 2222
Sulfur 70
Total number of atoms 23854
Formula = C7716H11845N2001O2222S70

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 242980 M-1 cm-1
assuming NO Cys residues appear as half cystines 241230 M-1 cm-1
assuming all Cys residues are reduced 241230 M-1 cm-1
assuming all pairs of Cys residues form cystines 242980 M-1 cm-1

Aliphatic index
Aliphatic index 83.09

Coding Region Translation Calculations
Codon Bias 0.277
Codon Adaptation Index 0.246
Frequency of Optimal Codons 0.568
Hydropathicity of Protein -0.124
Aromaticity Score 0.126