SLA2/YNL243W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 88 9.1%
Arg[R] 41 4.2%
Asn[N] 42 4.3%
Asp[D] 56 5.8%
Cys[C] 9 0.9%
Gln[Q] 84 8.7%
Glu[E] 74 7.6%
Gly[G] 23 2.4%
His[H] 23 2.4%
Ile[I] 53 5.5%
Leu[L] 103 10.6%
Lys[K] 57 5.9%
Met[M] 23 2.4%
Phe[F] 26 2.7%
Pro[P] 38 3.9%
Ser[S] 78 8.1%
Thr[T] 68 7.0%
Trp[W] 6 0.6%
Tyr[Y] 23 2.4%
Val[V] 53 5.5%
Total Length 968

Instability index
Instability index (II) 45.71
This classifies the protein as unstable

Atomic composition
Carbon 4764
Hydrogen 7648
Nitrogen 1326
Oxygen 1524
Sulfur 32
Total number of atoms 15294
Formula = C4764H7648N1326O1524S32

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 67770 M-1 cm-1
assuming NO Cys residues appear as half cystines 67270 M-1 cm-1
assuming all Cys residues are reduced 67270 M-1 cm-1
assuming all pairs of Cys residues form cystines 67770 M-1 cm-1

Aliphatic index
Aliphatic index 87.82

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000