APC1/YNL172W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 85 4.9%
Arg[R] 72 4.1%
Asn[N] 90 5.1%
Asp[D] 111 6.4%
Cys[C] 20 1.1%
Gln[Q] 59 3.4%
Glu[E] 99 5.7%
Gly[G] 95 5.4%
His[H] 32 1.8%
Ile[I] 132 7.6%
Leu[L] 206 11.8%
Lys[K] 108 6.2%
Met[M] 36 2.1%
Phe[F] 78 4.5%
Pro[P] 72 4.1%
Ser[S] 189 10.8%
Thr[T] 95 5.4%
Trp[W] 19 1.1%
Tyr[Y] 60 3.4%
Val[V] 90 5.1%
Total Length 1748

Instability index
Instability index (II) 42.75
This classifies the protein as unstable

Atomic composition
Carbon 8787
Hydrogen 13854
Nitrogen 2304
Oxygen 2662
Sulfur 56
Total number of atoms 27663
Formula = C8787H13854N2304O2662S56

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 195150 M-1 cm-1
assuming NO Cys residues appear as half cystines 193900 M-1 cm-1
assuming all Cys residues are reduced 193900 M-1 cm-1
assuming all pairs of Cys residues form cystines 195150 M-1 cm-1

Aliphatic index
Aliphatic index 95.21

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000