UTP14/YML093W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 53 5.9%
Arg[R] 56 6.2%
Asn[N] 63 7.0%
Asp[D] 89 9.9%
Cys[C] 0 0.0%
Gln[Q] 40 4.4%
Glu[E] 113 12.6%
Gly[G] 38 4.2%
His[H] 11 1.2%
Ile[I] 38 4.2%
Leu[L] 59 6.6%
Lys[K] 99 11.0%
Met[M] 26 2.9%
Phe[F] 18 2.0%
Pro[P] 25 2.8%
Ser[S] 74 8.2%
Thr[T] 39 4.3%
Trp[W] 7 0.8%
Tyr[Y] 12 1.3%
Val[V] 39 4.3%
Total Length 899

Instability index
Instability index (II) 51.26
This classifies the protein as unstable

Atomic composition
Carbon 4361
Hydrogen 7062
Nitrogen 1298
Oxygen 1532
Sulfur 26
Total number of atoms 14279
Formula = C4361H7062N1298O1532S26

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 56380 M-1 cm-1

Aliphatic index
Aliphatic index 60.56

Coding Region Translation Calculations
Codon Bias 0.192
Codon Adaptation Index 0.225
Frequency of Optimal Codons 0.528
Hydropathicity of Protein -1.279
Aromaticity Score 0.041