SCY1/YGL083W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 26 3.2%
Arg[R] 21 2.6%
Asn[N] 46 5.7%
Asp[D] 40 5.0%
Cys[C] 8 1.0%
Gln[Q] 30 3.7%
Glu[E] 46 5.7%
Gly[G] 26 3.2%
His[H] 13 1.6%
Ile[I] 54 6.7%
Leu[L] 92 11.4%
Lys[K] 69 8.6%
Met[M] 15 1.9%
Phe[F] 46 5.7%
Pro[P] 50 6.2%
Ser[S] 89 11.1%
Thr[T] 56 7.0%
Trp[W] 6 0.7%
Tyr[Y] 25 3.1%
Val[V] 46 5.7%
Total Length 804

Instability index
Instability index (II) 46.68
This classifies the protein as unstable

Atomic composition
Carbon 4123
Hydrogen 6500
Nitrogen 1044
Oxygen 1223
Sulfur 23
Total number of atoms 12913
Formula = C4123H6500N1044O1223S23

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming all Cys residues are reduced 70250 M-1 cm-1
assuming all pairs of Cys residues form cystines 70750 M-1 cm-1

Aliphatic index
Aliphatic index 90.65

Coding Region Translation Calculations
Codon Bias 0.073
Codon Adaptation Index 0.156
Frequency of Optimal Codons 0.455
Hydropathicity of Protein -0.250
Aromaticity Score 0.096