SWR1/YDR334W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 78 5.2%
Arg[R] 85 5.6%
Asn[N] 82 5.4%
Asp[D] 120 7.9%
Cys[C] 14 0.9%
Gln[Q] 72 4.8%
Glu[E] 132 8.7%
Gly[G] 60 4.0%
His[H] 41 2.7%
Ile[I] 66 4.4%
Leu[L] 158 10.4%
Lys[K] 137 9.0%
Met[M] 24 1.6%
Phe[F] 63 4.2%
Pro[P] 44 2.9%
Ser[S] 115 7.6%
Thr[T] 83 5.5%
Trp[W] 10 0.7%
Tyr[Y] 47 3.1%
Val[V] 83 5.5%
Total Length 1514

Instability index
Instability index (II) 44.03
This classifies the protein as unstable

Atomic composition
Carbon 7678
Hydrogen 12166
Nitrogen 2152
Oxygen 2418
Sulfur 38
Total number of atoms 24452
Formula = C7678H12166N2152O2418S38

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 125905 M-1 cm-1
assuming NO Cys residues appear as half cystines 125030 M-1 cm-1
assuming all Cys residues are reduced 125030 M-1 cm-1
assuming all pairs of Cys residues form cystines 125905 M-1 cm-1

Aliphatic index
Aliphatic index 78.75

Coding Region Translation Calculations
Codon Bias 0.056
Codon Adaptation Index 0.145
Frequency of Optimal Codons 0.442
Hydropathicity of Protein -0.753
Aromaticity Score 0.079