TAF10/YDR167W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 19 9.2%
Arg[R] 10 4.9%
Asn[N] 13 6.3%
Asp[D] 22 10.7%
Cys[C] 0 0.0%
Gln[Q] 17 8.3%
Glu[E] 15 7.3%
Gly[G] 10 4.9%
His[H] 1 0.5%
Ile[I] 9 4.4%
Leu[L] 12 5.8%
Lys[K] 12 5.8%
Met[M] 4 1.9%
Phe[F] 8 3.9%
Pro[P] 8 3.9%
Ser[S] 14 6.8%
Thr[T] 9 4.4%
Trp[W] 0 0.0%
Tyr[Y] 7 3.4%
Val[V] 16 7.8%
Total Length 206

Instability index
Instability index (II) 43.14
This classifies the protein as unstable

Atomic composition
Carbon 994
Hydrogen 1562
Nitrogen 280
Oxygen 341
Sulfur 4
Total number of atoms 3181
Formula = C994H1562N280O341S4

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 10430 M-1 cm-1

Aliphatic index
Aliphatic index 71.50

Coding Region Translation Calculations
Codon Bias -0.072
Codon Adaptation Index 0.096
Frequency of Optimal Codons 0.371
Hydropathicity of Protein -0.754
Aromaticity Score 0.073