UFD2/YDL190C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 59 6.1%
Arg[R] 42 4.4%
Asn[N] 57 5.9%
Asp[D] 60 6.2%
Cys[C] 10 1.0%
Gln[Q] 34 3.5%
Glu[E] 71 7.4%
Gly[G] 35 3.6%
His[H] 18 1.9%
Ile[I] 65 6.8%
Leu[L] 109 11.3%
Lys[K] 69 7.2%
Met[M] 18 1.9%
Phe[F] 67 7.0%
Pro[P] 44 4.6%
Ser[S] 71 7.4%
Thr[T] 45 4.7%
Trp[W] 1 0.1%
Tyr[Y] 35 3.6%
Val[V] 51 5.3%
Total Length 961

Instability index
Instability index (II) 42.86
This classifies the protein as unstable

Atomic composition
Carbon 4975
Hydrogen 7762
Nitrogen 1284
Oxygen 1466
Sulfur 28
Total number of atoms 15515
Formula = C4975H7762N1284O1466S28

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 58275 M-1 cm-1
assuming NO Cys residues appear as half cystines 57650 M-1 cm-1
assuming all Cys residues are reduced 57650 M-1 cm-1
assuming all pairs of Cys residues form cystines 58275 M-1 cm-1

Aliphatic index
Aliphatic index 92.14

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000