CDC26/YFR036W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 6 4.8%
Arg[R] 4 3.2%
Asn[N] 17 13.7%
Asp[D] 17 13.7%
Cys[C] 0 0.0%
Gln[Q] 7 5.6%
Glu[E] 7 5.6%
Gly[G] 3 2.4%
His[H] 6 4.8%
Ile[I] 6 4.8%
Leu[L] 10 8.1%
Lys[K] 6 4.8%
Met[M] 2 1.6%
Phe[F] 3 2.4%
Pro[P] 2 1.6%
Ser[S] 12 9.7%
Thr[T] 10 8.1%
Trp[W] 0 0.0%
Tyr[Y] 3 2.4%
Val[V] 3 2.4%
Total Length 124

Instability index
Instability index (II) 50.46
This classifies the protein as unstable

Atomic composition
Carbon 587
Hydrogen 914
Nitrogen 178
Oxygen 222
Sulfur 2
Total number of atoms 1903
Formula = C587H914N178O222S2

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 4470 M-1 cm-1

Aliphatic index
Aliphatic index 62.18

Coding Region Translation Calculations
Codon Bias 0.092
Codon Adaptation Index 0.134
Frequency of Optimal Codons 0.484
Hydropathicity of Protein -1.233
Aromaticity Score 0.048