MCH2/YKL221W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 37 7.8%
Arg[R] 18 3.8%
Asn[N] 17 3.6%
Asp[D] 14 3.0%
Cys[C] 8 1.7%
Gln[Q] 13 2.7%
Glu[E] 12 2.5%
Gly[G] 47 9.9%
His[H] 11 2.3%
Ile[I] 43 9.1%
Leu[L] 63 13.3%
Lys[K] 15 3.2%
Met[M] 11 2.3%
Phe[F] 31 6.6%
Pro[P] 10 2.1%
Ser[S] 37 7.8%
Thr[T] 25 5.3%
Trp[W] 12 2.5%
Tyr[Y] 20 4.2%
Val[V] 29 6.1%
Total Length 473

Instability index
Instability index (II) 32.56
This classifies the protein as stable

Atomic composition
Carbon 2430
Hydrogen 3736
Nitrogen 606
Oxygen 638
Sulfur 19
Total number of atoms 7429
Formula = C2430H3736N606O638S19

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 96300 M-1 cm-1
assuming NO Cys residues appear as half cystines 95800 M-1 cm-1
assuming all Cys residues are reduced 95800 M-1 cm-1
assuming all pairs of Cys residues form cystines 96300 M-1 cm-1

Aliphatic index
Aliphatic index 113.00

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000