YIL080W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 86 5.5%
Arg[R] 101 6.4%
Asn[N] 91 5.8%
Asp[D] 84 5.4%
Cys[C] 18 1.1%
Gln[Q] 69 4.4%
Glu[E] 88 5.6%
Gly[G] 53 3.4%
His[H] 48 3.1%
Ile[I] 108 6.9%
Leu[L] 153 9.8%
Lys[K] 115 7.3%
Met[M] 31 2.0%
Phe[F] 64 4.1%
Pro[P] 92 5.9%
Ser[S] 91 5.8%
Thr[T] 125 8.0%
Trp[W] 11 0.7%
Tyr[Y] 66 4.2%
Val[V] 75 4.8%
Total Length 1569

Instability index
Instability index (II) 43.05
This classifies the protein as unstable

Atomic composition
Carbon 8107
Hydrogen 12822
Nitrogen 2254
Oxygen 2356
Sulfur 49
Total number of atoms 25588
Formula = C8107H12822N2254O2356S49

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 159965 M-1 cm-1
assuming NO Cys residues appear as half cystines 158840 M-1 cm-1
assuming all Cys residues are reduced 158840 M-1 cm-1
assuming all pairs of Cys residues form cystines 159965 M-1 cm-1

Aliphatic index
Aliphatic index 84.22

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000