YHR095W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 9 5.5%
Arg[R] 8 4.9%
Asn[N] 6 3.7%
Asp[D] 2 1.2%
Cys[C] 6 3.7%
Gln[Q] 7 4.3%
Glu[E] 6 3.7%
Gly[G] 3 1.8%
His[H] 6 3.7%
Ile[I] 12 7.3%
Leu[L] 19 11.6%
Lys[K] 23 14.0%
Met[M] 5 3.0%
Phe[F] 10 6.1%
Pro[P] 7 4.3%
Ser[S] 16 9.8%
Thr[T] 6 3.7%
Trp[W] 2 1.2%
Tyr[Y] 3 1.8%
Val[V] 8 4.9%
Total Length 164

Instability index
Instability index (II) 47.70
This classifies the protein as unstable

Atomic composition
Carbon 867
Hydrogen 1410
Nitrogen 238
Oxygen 219
Sulfur 11
Total number of atoms 2745
Formula = C867H1410N238O219S11

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 14355 M-1 cm-1
assuming NO Cys residues appear as half cystines 13980 M-1 cm-1
assuming all Cys residues are reduced 15470 M-1 cm-1
assuming all pairs of Cys residues form cystines 15845 M-1 cm-1

Aliphatic index
Aliphatic index 93.35

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000