ERG7/YHR072W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 45 6.2%
Arg[R] 31 4.2%
Asn[N] 28 3.8%
Asp[D] 30 4.1%
Cys[C] 15 2.1%
Gln[Q] 21 2.9%
Glu[E] 51 7.0%
Gly[G] 48 6.6%
His[H] 20 2.7%
Ile[I] 42 5.7%
Leu[L] 66 9.0%
Lys[K] 41 5.6%
Met[M] 15 2.1%
Phe[F] 42 5.7%
Pro[P] 41 5.6%
Ser[S] 51 7.0%
Thr[T] 43 5.9%
Trp[W] 17 2.3%
Tyr[Y] 40 5.5%
Val[V] 44 6.0%
Total Length 731

Instability index
Instability index (II) 39.76
This classifies the protein as stable

Atomic composition
Carbon 3818
Hydrogen 5763
Nitrogen 971
Oxygen 1077
Sulfur 30
Total number of atoms 11659
Formula = C3818H5763N971O1077S30

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 153975 M-1 cm-1
assuming NO Cys residues appear as half cystines 153100 M-1 cm-1
assuming all Cys residues are reduced 153100 M-1 cm-1
assuming all pairs of Cys residues form cystines 153975 M-1 cm-1

Aliphatic index
Aliphatic index 81.23

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000