CDC39/YCR093W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 124 5.9%
Arg[R] 84 4.0%
Asn[N] 125 5.9%
Asp[D] 111 5.3%
Cys[C] 13 0.6%
Gln[Q] 130 6.2%
Glu[E] 127 6.0%
Gly[G] 58 2.8%
His[H] 34 1.6%
Ile[I] 163 7.7%
Leu[L] 275 13.0%
Lys[K] 134 6.4%
Met[M] 44 2.1%
Phe[F] 115 5.5%
Pro[P] 87 4.1%
Ser[S] 159 7.5%
Thr[T] 124 5.9%
Trp[W] 19 0.9%
Tyr[Y] 48 2.3%
Val[V] 134 6.4%
Total Length 2108

Instability index
Instability index (II) 42.75
This classifies the protein as unstable

Atomic composition
Carbon 10870
Hydrogen 17298
Nitrogen 2836
Oxygen 3171
Sulfur 57
Total number of atoms 34232
Formula = C10870H17298N2836O3171S57

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 176770 M-1 cm-1
assuming NO Cys residues appear as half cystines 176020 M-1 cm-1
assuming all Cys residues are reduced 176020 M-1 cm-1
assuming all pairs of Cys residues form cystines 176770 M-1 cm-1

Aliphatic index
Aliphatic index 105.35

Coding Region Translation Calculations
Codon Bias 0.131
Codon Adaptation Index 0.169
Frequency of Optimal Codons 0.487
Hydropathicity of Protein -0.089
Aromaticity Score 0.086