CMD1/YBR109C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 12 8.2%
Arg[R] 3 2.0%
Asn[N] 9 6.1%
Asp[D] 12 8.2%
Cys[C] 0 0.0%
Gln[Q] 6 4.1%
Glu[E] 18 12.2%
Gly[G] 8 5.4%
His[H] 2 1.4%
Ile[I] 8 5.4%
Leu[L] 18 12.2%
Lys[K] 8 5.4%
Met[M] 5 3.4%
Phe[F] 8 5.4%
Pro[P] 1 0.7%
Ser[S] 18 12.2%
Thr[T] 4 2.7%
Trp[W] 0 0.0%
Tyr[Y] 0 0.0%
Val[V] 7 4.8%
Total Length 147

Instability index
Instability index (II) 44.43
This classifies the protein as unstable

Atomic composition
Carbon 697
Hydrogen 1111
Nitrogen 183
Oxygen 245
Sulfur 5
Total number of atoms 2241
Formula = C697H1111N183O245S5

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours


Aliphatic index
Aliphatic index 90.95

Coding Region Translation Calculations
Codon Bias 0.164
Codon Adaptation Index 0.220
Frequency of Optimal Codons 0.500
Hydropathicity of Protein -0.295
Aromaticity Score 0.054