TEL1/YBL088C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 120 4.3%
Arg[R] 109 3.9%
Asn[N] 170 6.1%
Asp[D] 149 5.3%
Cys[C] 49 1.8%
Gln[Q] 112 4.0%
Glu[E] 179 6.4%
Gly[G] 98 3.5%
His[H] 47 1.7%
Ile[I] 206 7.4%
Leu[L] 357 12.8%
Lys[K] 207 7.4%
Met[M] 59 2.1%
Phe[F] 157 5.6%
Pro[P] 84 3.0%
Ser[S] 251 9.0%
Thr[T] 140 5.0%
Trp[W] 41 1.5%
Tyr[Y] 109 3.9%
Val[V] 143 5.1%
Total Length 2787

Instability index
Instability index (II) 38.93
This classifies the protein as stable

Atomic composition
Carbon 14578
Hydrogen 22814
Nitrogen 3738
Oxygen 4226
Sulfur 108
Total number of atoms 45464
Formula = C14578H22814N3738O4226S108

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 390910 M-1 cm-1
assuming NO Cys residues appear as half cystines 387910 M-1 cm-1
assuming all Cys residues are reduced 387910 M-1 cm-1
assuming all pairs of Cys residues form cystines 390910 M-1 cm-1

Aliphatic index
Aliphatic index 97.97

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000