BDH1/YAL060W Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 24 6.3%
Arg[R] 8 2.1%
Asn[N] 10 2.6%
Asp[D] 22 5.8%
Cys[C] 11 2.9%
Gln[Q] 10 2.6%
Glu[E] 25 6.5%
Gly[G] 36 9.4%
His[H] 17 4.5%
Ile[I] 28 7.3%
Leu[L] 27 7.1%
Lys[K] 31 8.1%
Met[M] 11 2.9%
Phe[F] 14 3.7%
Pro[P] 19 5.0%
Ser[S] 26 6.8%
Thr[T] 16 4.2%
Trp[W] 5 1.3%
Tyr[Y] 6 1.6%
Val[V] 36 9.4%
Total Length 382

Instability index
Instability index (II) 36.17
This classifies the protein as stable

Atomic composition
Carbon 1853
Hydrogen 2930
Nitrogen 496
Oxygen 545
Sulfur 22
Total number of atoms 5846
Formula = C1853H2930N496O545S22

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 37065 M-1 cm-1
assuming NO Cys residues appear as half cystines 36440 M-1 cm-1
assuming all Cys residues are reduced 36440 M-1 cm-1
assuming all pairs of Cys residues form cystines 37065 M-1 cm-1

Aliphatic index
Aliphatic index 89.76

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000