DRS2/YAL026C Additional Physico-chemical Properties Help

Physico-chemical properties were determined using the ProtParam tool available through ExPASy to analyze the primary protein sequence for atomic composition, extinction coefficient, estimated half-life, instability index and aliphatic index. Transcript translation calculations were determined using CodonW.


A.A. Composition
Ala[A] 87 6.4%
Arg[R] 58 4.3%
Asn[N] 82 6.1%
Asp[D] 85 6.3%
Cys[C] 13 1.0%
Gln[Q] 47 3.5%
Glu[E] 89 6.6%
Gly[G] 76 5.6%
His[H] 27 2.0%
Ile[I] 109 8.0%
Leu[L] 126 9.3%
Lys[K] 78 5.8%
Met[M] 28 2.1%
Phe[F] 79 5.8%
Pro[P] 45 3.3%
Ser[S] 97 7.2%
Thr[T] 84 6.2%
Trp[W] 18 1.3%
Tyr[Y] 52 3.8%
Val[V] 75 5.5%
Total Length 1355

Instability index
Instability index (II) 36.40
This classifies the protein as stable

Atomic composition
Carbon 6932
Hydrogen 10726
Nitrogen 1808
Oxygen 2066
Sulfur 41
Total number of atoms 21573
Formula = C6932H10726N1808O2066S41

Estimated half-life
Escherichia coli (in vivo) >10 hours
mammalian reticulocytes (in vitro) 30 hours
yeast (in vivo) >20 hours

Extinction Coefficients at 280 nm
assuming ALL Cys residues appear as half cystines 178720 M-1 cm-1
assuming NO Cys residues appear as half cystines 177970 M-1 cm-1
assuming all Cys residues are reduced 176480 M-1 cm-1
assuming all pairs of Cys residues form cystines 177230 M-1 cm-1

Aliphatic index
Aliphatic index 90.11

Coding Region Translation Calculations
Codon Bias 0.000
Codon Adaptation Index 0.000
Frequency of Optimal Codons 0.000
Hydropathicity of Protein 0.000
Aromaticity Score 0.000