MTM1/YGR257C Protein Information

MTM1 BASIC PROTEIN INFORMATION

Standard Name	Mtm1p
Systematic Name	Ygr257cp
ORF Classification	Verified
Description	Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor ( 1 )
Name Description	Manganese Trafficking factor for Mitochondrial SOD2 1

Experimental Data
Molecules/cell	538 2

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	366
Molecular Weight (Da)	40,763
Isoelectric Point (pI)	10.12

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Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Mtm1p (InterPro)
Physical Interactions	There are 2 total curated physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| PSI-BLAST \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
Secondary Structure Prediction	GCG:PepPlot \| GCG:PepStruct \| GCG:Helical Wheel
External Sequence Databases	EBI: P53320 \| UPI000013AFC4 MIPS: YGR257C NCBI: NP_011773.1 \| 6321696

Amino Acid Sequence (or in FASTA format)
1 MSDRNTSNSL TLKERMLSAG AGSVLTSLIL TPMDVVRIRL QQQQMIPDCS 51 CDGAAEVPNA VSSGSKMKTF TNVGGQNLNN AKIFWESACF QELHCKNSSL 101 KFNGTLEAFT KIASVEGITS LWRGISLTLL MAIPANMVYF SGYEYIRDVS 151 PIASTYPTLN PLFCGAIARV FAATSIAPLE LVKTKLQSIP RSSKSTKTWM 201 MVKDLLNETR QEMKMVGPSR ALFKGLEITL WRDVPFSAIY WSSYELCKER 251 LWLDSTRFAS KDANWVHFIN SFASGCISGM IAAICTHPFD VGKTRWQISM 301 MNNSDPKGGN RSRNMFKFLE TIWRTEGLAA LYTGLAARVI KIRPSCAIMI 351 SSYEISKKVF GNKLHQ*

Amino Acid Sequence (or in FASTA format)

       1  MSDRNTSNSL TLKERMLSAG AGSVLTSLIL TPMDVVRIRL QQQQMIPDCS
      51  CDGAAEVPNA VSSGSKMKTF TNVGGQNLNN AKIFWESACF QELHCKNSSL
     101  KFNGTLEAFT KIASVEGITS LWRGISLTLL MAIPANMVYF SGYEYIRDVS
     151  PIASTYPTLN PLFCGAIARV FAATSIAPLE LVKTKLQSIP RSSKSTKTWM
     201  MVKDLLNETR QEMKMVGPSR ALFKGLEITL WRDVPFSAIY WSSYELCKER
     251  LWLDSTRFAS KDANWVHFIN SFASGCISGM IAAICTHPFD VGKTRWQISM
     301  MNNSDPKGGN RSRNMFKFLE TIWRTEGLAA LYTGLAARVI KIRPSCAIMI
     351  SSYEISKKVF GNKLHQ*

EXTERNAL LINKS for Mtm1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	Organelle DB (UMich)
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YGAC Triples
Candida (CGD)	BioPIXIE	MIPS
Candida (CandidaDB)	CYC2008 (complexes)	Pfam domains
YGOB	DIP	PhosphoPep Database
YOGY		YeastRC Structure Prediction (Seattle)

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for Mtm1p ]

1)	Luk E, et al. (2003) Manganese activation of superoxide dismutase 2 in Saccharomyces cerevisiae requires MTM1, a member of the mitochondrial carrier family. Proc Natl Acad Sci U S A 100(18):10353-7
2)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41

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