GDA1/YEL042W Protein Information Help

GDA1 BASIC PROTEIN INFORMATION

Standard Name Gda1p
Systematic Name Yel042wp
ORF Classification Verified
Description Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate ( 1 )
Name Description Guanosine DiphosphatAse
Experimental Data
Molecules/cell 8680 2
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 518
Molecular Weight (Da) 56,821
Isoelectric Point (pI) 5.07

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Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Gda1p (InterPro)
Transmembrane Domains There are 1 total predicted transmembrane domains (TMHMM)
Signal Peptide(s) There are 1 total predicted predicted signal peptide(s) (SignalP)
Physical Interactions There are 9 total curated physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | PSI-BLAST | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
Secondary Structure Prediction GCG:PepPlot | GCG:PepStruct | GCG:Helical Wheel
External Sequence Databases EBI: P32621 | UPI000012B37F
MIPS: YEL042W
NCBI: NP_010872.1 | 6320793
GenBank/EMBL/DDBJ: AY723798
External Classifications EC: 3.6.1.42 [Guanosine-diphosphatase]
Amino Acid Sequence (or in FASTA format)
 
       1  MAPIFRNYRF AIGAFAVIML ILLIKTSSIG PPSIARTVTP NASIPKTPED
      51  ISILPVNDEP GYLQDSKTEQ NYPELADAVK SQTSQTCSEE HKYVIMIDAG
     101  STGSRVHIYK FDVCTSPPTL LDEKFDMLEP GLSSFDTDSV GAANSLDPLL
     151  KVAMNYVPIK ARSCTPVAVK ATAGLRLLGD AKSSKILSAV RDHLEKDYPF
     201  PVVEGDGVSI MGGDEEGVFA WITTNYLLGN IGANGPKLPT AAVFDLGGGS
     251  TQIVFEPTFP INEKMVDGEH KFDLKFGDEN YTLYQFSHLG YGLKEGRNKV
     301  NSVLVENALK DGKILKGDNT KTHQLSSPCL PPKVNATNEK VTLESKETYT
     351  IDFIGPDEPS GAQCRFLTDE ILNKDAQCQS PPCSFNGVHQ PSLVRTFKES
     401  NDIYIFSYFY DRTRPLGMPL SFTLNELNDL ARIVCKGEET WNSVFSGIAG
     451  SLDELESDSH FCLDLSFQVS LLHTGYDIPL QRELRTGKKI ANKEIGWCLG
     501  ASLPLLKADN WKCKIQSA*

EXTERNAL LINKS for Gda1p

Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YGAC Triples
Ashbya (AGD) BOND GPMdb (Mass Spec.)
Candida (CGD) BioPIXIE MIPS
Candida (CandidaDB) CYC2008 (complexes) Pfam domains
YGOB DIP PhosphoPep Database
YOGY YeastRC Mass Spec (Seattle) YeastRC Structure Prediction (Seattle)

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for Gda1p ]

1) Berninsone P, et al.  (1994) The Golgi guanosine diphosphatase is required for transport of GDP-mannose into the lumen of Saccharomyces cerevisiae Golgi vesicles. J Biol Chem 269(1):207-11
2) Ghaemmaghami S, et al.  (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41