REP1/R0020C Protein Information

Standard Name	Rep1p 1
Systematic Name	R0020cp
ORF Classification	Verified
Description	Master regulator that acts in concert with Rep2p to regulate transcript levels of the FLP1 gene that promotes plasmid copy amplification; autoregulates levels of its own transcript (2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	373
Molecular Weight (Da)	43,231
Isoelectric Point (pI)	6.39

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Post-translational Modifications	PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Rep1p (InterPro)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI0000133684 \| P03871 MIPS: R0020C NCBI: 11466069 \| 132332 \| 172192 \| 172380 \| 4307 \| NP_040489.1 GenBank/EMBL/DDBJ: J01347 \| M31942 \| X55437

Amino Acid Sequence (or in FASTA format)
1 MNGERLLACI KQCIMQHFQP MVYDESRCVI ETTRGTFPVP DNYKKYKTLA 51 FAFVGHVLNT DDTPVIEKEL DWPDPALVYN TIVDRIINHP ELSQFISVAF 101 ISQLKATIGE GLDINVKGTL NRRGKGIRRP KGVFFRYMES PFVNTKVTAF 151 FSYLRDYNKI ASEYHNNTKF ILTFSCQAYW ASGPNFSALK NVIRCSIIHE 201 YISKFVEREQ DKGHIGDQEL PPEEDPSREL NNVQHEVNSL TEQDAEADEG 251 LWGEIDSLCE KWQSEAEDQT EAEIIADRII GNSQRMANLK IRRTKFKSVL 301 YHILKELIQS QGTVKVYRGS SFSHDSIKIS LHYEEQHITA VWVYLTVKFE 351 EHWKPVDVEV EFRCKFKERK VDG*

Amino Acid Sequence (or in FASTA format)

       1  MNGERLLACI KQCIMQHFQP MVYDESRCVI ETTRGTFPVP DNYKKYKTLA
      51  FAFVGHVLNT DDTPVIEKEL DWPDPALVYN TIVDRIINHP ELSQFISVAF
     101  ISQLKATIGE GLDINVKGTL NRRGKGIRRP KGVFFRYMES PFVNTKVTAF
     151  FSYLRDYNKI ASEYHNNTKF ILTFSCQAYW ASGPNFSALK NVIRCSIIHE
     201  YISKFVEREQ DKGHIGDQEL PPEEDPSREL NNVQHEVNSL TEQDAEADEG
     251  LWGEIDSLCE KWQSEAEDQT EAEIIADRII GNSQRMANLK IRRTKFKSVL
     301  YHILKELIQS QGTVKVYRGS SFSHDSIKIS LHYEEQHITA VWVYLTVKFE
     351  EHWKPVDVEV EFRCKFKERK VDG*

external links for Rep1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BOND	SCOP Superfamily	YPL+
Ashbya (AGD)	BioPIXIE	GPMdb (Mass Spec.)	YeastGFP
YGOB	CYC2008 (complexes)	MIPS
YOGY	Complexome	Pfam domains
	DIP
	GeneMANIA

References cited on this page View Complete Literature Guide for Rep1p

1)	Jayaram M, et al. (1983) The yeast plasmid 2mu circle encodes components required for its high copy propagation. Cell 34(1):95-104
2)	Veit BE and Fangman WL (1988) Copy number and partition of the Saccharomyces cerevisiae 2 micron plasmid controlled by transcription regulators. Mol Cell Biol 8(11):4949-57