FLP1/R0010W Protein Information

Standard Name	Flp1p
Systematic Name	R0010wp
ORF Classification	Verified
Description	Site-specific recombinase encoded on the 2-micron plasmid, required for 2-micron plasmid propagation as part of a plasmid amplification system that compensates for any copy number decreases caused by missegregation events (1, 2)

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	423
Molecular Weight (Da)	48,619
Isoelectric Point (pI)	10.17

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Post-translational Modifications	PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Flp1p (InterPro)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000011EE1B \| P03870 MIPS: R0010W NCBI: 10120585 \| 10120586 \| 10120587 \| 10120588 \| 11466068 \| 120357 \| 172191 \| 28373601 \| 28373602 \| 28373603 \| 28373604 \| 31615974 \| 31615975 \| 31615976 \| 31615977 \| NP_040488.1 GenBank/EMBL/DDBJ: J01347

Amino Acid Sequence (or in FASTA format)
1 MPQFGILCKT PPKVLVRQFV ERFERPSGEK IALCAAELTY LCWMITHNGT 51 AIKRATFMSY NTIISNSLSF DIVNKSLQFK YKTQKATILE ASLKKLIPAW 101 EFTIIPYYGQ KHQSDITDIV SSLQLQFESS EEADKGNSHS KKMLKALLSE 151 GESIWEITEK ILNSFEYTSR FTKTKTLYQF LFLATFINCG RFSDIKNVDP 201 KSFKLVQNKY LGVIIQCLVT ETKTSVSRHI YFFSARGRID PLVYLDEFLR 251 NSEPVLKRVN RTGNSSSNKQ EYQLLKDNLV RSYNKALKKN APYSIFAIKN 301 GPKSHIGRHL MTSFLSMKGL TELTNVVGNW SDKRASAVAR TTYTHQITAI 351 PDHYFALVSR YYAYDPISKE MIALKDETNP IEEWQHIEQL KGSAEGSIRY 401 PAWNGIISQE VLDYLSSYIN RRI*

Amino Acid Sequence (or in FASTA format)

       1  MPQFGILCKT PPKVLVRQFV ERFERPSGEK IALCAAELTY LCWMITHNGT
      51  AIKRATFMSY NTIISNSLSF DIVNKSLQFK YKTQKATILE ASLKKLIPAW
     101  EFTIIPYYGQ KHQSDITDIV SSLQLQFESS EEADKGNSHS KKMLKALLSE
     151  GESIWEITEK ILNSFEYTSR FTKTKTLYQF LFLATFINCG RFSDIKNVDP
     201  KSFKLVQNKY LGVIIQCLVT ETKTSVSRHI YFFSARGRID PLVYLDEFLR
     251  NSEPVLKRVN RTGNSSSNKQ EYQLLKDNLV RSYNKALKKN APYSIFAIKN
     301  GPKSHIGRHL MTSFLSMKGL TELTNVVGNW SDKRASAVAR TTYTHQITAI
     351  PDHYFALVSR YYAYDPISKE MIALKDETNP IEEWQHIEQL KGSAEGSIRY
     401  PAWNGIISQE VLDYLSSYIN RRI*

external links for Flp1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BOND	SCOP Superfamily	YPL+
Ashbya (AGD)	BioPIXIE	GPMdb (Mass Spec.)	YeastGFP
YGOB	CYC2008 (complexes)	MIPS
YOGY	Complexome	Pfam domains
	GeneMANIA

References cited on this page View Complete Literature Guide for Flp1p

1)	Ghosh SK, et al. (2006) Mechanisms for chromosome and plasmid segregation. Annu Rev Biochem 75:211-41
2)	Luetke KH and Sadowski PD (1998) Determinants of the position of a Flp-induced DNA bend. Nucleic Acids Res 26(6):1401-7