VMA9/YCL005W-A Protein Information 
| Standard Name | Vma9p 1 |
|---|---|
| Systematic Name | Ycl005w-ap |
| Alias | Cwh36p 2 , Ldb10p |
| ORF Classification | Verified |
| Description | Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis (1, 3) |
| Name Description | Vacuolar Membrane Atpase 1 |
| Click on image for expanded interactive view |
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| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Vma9p (InterPro) |
| Transmembrane Domains | There are 2 total predicted transmembrane domains (TMHMM) |
| Signal Peptide(s) | There are 1 total predicted predicted signal peptide(s) (SignalP) |
| Physical Interactions | There are 7 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI000034F5C5 | Q3E7B6 MIPS: YCL005W-A NCBI: 41629681 | 85541987 | NP_958835.1 | NM_001184518.1 GenBank/EMBL/DDBJ: DAA07474.1 | X59720 |
| External Classifications | EC: 3.6.3.14 [H(+)-transporting two-sector ATPase] |
external links for Vma9p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | YPL+ |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YeastGFP |
| Candida (CGD) | BioPIXIE | MIPS | |
| YGOB | CYC2008 (complexes) | Pfam domains | |
| YOGY | Complexome | ||
| GeneMANIA |
References cited on this page View Complete Literature Guide for Vma9p
| 1) | Sambade M and Kane PM (2004) The yeast vacuolar proton-translocating ATPase contains a subunit homologous to the Manduca sexta and bovine e subunits that is essential for function. J Biol Chem 279(17):17361-5 |
| 2) | Davis-Kaplan SR, et al. (2004) Genome-wide analysis of iron-dependent growth reveals a novel yeast gene required for vacuolar acidification. J Biol Chem 279(6):4322-9 |
| 3) | Compton MA, et al. (2006) Vma9p (subunit e) is an integral membrane V0 subunit of the yeast V-ATPase. J Biol Chem 281(22):15312-9 |
