COA3/YJL062W-A Protein Information 
| Standard Name | Coa3p 1 |
|---|---|
| Systematic Name | Yjl062w-ap |
| Alias | Rrg10p 2 , Cox25p 3 |
| ORF Classification | Verified |
| Description | Mitochondrial inner membrane protein that participates in regulation of COX1 translation, Cox1p stabilization, and cytochrome oxidase assembly (1, 2, 3, 4) |
| Name Description | Cytochrome Oxidase Assembly 1 |
| Experimental Data | |
|---|---|
| Molecules/cell | 2530 5 |
| Click on image for expanded interactive view |
|---|
| Post-translational Modifications | PhosphoGRID | PhosphoPep Database |
|---|---|
| Domains/motifs | See the graphical view and list of proteins that share domains/motifs in common with Coa3p (InterPro) |
| Transmembrane Domains | There are 1 total predicted transmembrane domains (TMHMM) |
| Signal Peptide(s) | There are 1 total predicted predicted signal peptide(s) (SignalP) |
| Physical Interactions | There are 31 total physical interactions (BioGRID) |
| Homologs | PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer |
| External Sequence Databases |
EBI: UPI0000168362 | Q3E7B2 MIPS: YJL062W-A NCBI: 110288066 | 398364487 | NP_076894.3 GenBank/EMBL/DDBJ: DAA08735.1 | Z49338 |
external links for Coa3p
| Homologs | Interaction Resources | Protein databases/Other | Localization Resources |
|---|---|---|---|
| BLASTP (NCBI) | BioGRID | SCOP Superfamily | YPL+ |
| Ashbya (AGD) | BOND | GPMdb (Mass Spec.) | YeastGFP |
| Candida (CGD) | BioPIXIE | MIPS | YeastRC Public Image Repository |
| Candida (CandidaDB) | CYC2008 (complexes) | Pfam domains | |
| YGOB | Complexome | ||
| YOGY | GeneMANIA |
References cited on this page View Complete Literature Guide for Coa3p
| 1) | Mick DU, et al. (2010) Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria. J Cell Biol 191(1):141-54 |
| 2) | Merz S and Westermann B (2009) Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae. Genome Biol 10(9):R95 |
| 3) | Fontanesi F, et al. (2011) Cox25 Teams Up with Mss51, Ssc1, and Cox14 to Regulate Mitochondrial Cytochrome c Oxidase Subunit 1 Expression and Assembly in Saccharomyces cerevisiae. J Biol Chem 286(1):555-66 |
| 4) | Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 |
| 5) | Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41 |
