EFG1/YGR271C-A Protein Information

Standard Name	Efg1p 1
Systematic Name	Ygr271c-ap
Alias	Ygr272cp
ORF Classification	Verified
Description	Essential protein required for maturation of 18S rRNA; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus (1, 2, 3)
Name Description	Exit From G1 1

Experimental Data
Molecules/cell	2840 4

Predicted Sequence	Formatted Sequence or sequence in FASTA format
Length (a.a.)	233
Molecular Weight (Da)	27,121
Isoelectric Point (pI)	10.27

Click on image for expanded interactive view

Post-translational Modifications	PhosphoGRID \| PhosphoPep Database
Domains/motifs	See the graphical view and list of proteins that share domains/motifs in common with Efg1p (InterPro)
Physical Interactions	There are 9 total physical interactions (BioGRID)
Homologs	PDB Homologs \| BLASTP \| BLASTP v. fungi \| Fungal Alignment \| Synteny Viewer
External Sequence Databases	EBI: UPI000158E64A MIPS: YGR271C-A NCBI: 1323495 \| 187608872 \| 2104895 \| 398366365 \| 45270916 \| NP_076891.4 GenBank/EMBL/DDBJ: DAA08360.1 \| AY558513 \| X84098 \| Z73057

Amino Acid Sequence (or in FASTA format)
1 MAKLQRKRSK ALGSSLEMSQ IMDAGTNKIK RRIRDLERLL KKKKDILPST 51 VIIEKERNLQ ALRLELQNNE LKNKIKANAK KYHMVRFFEK KKALRKYNRL 101 LKKIKESGAD DKDLQQKLRA TKIELCYVIN FPKTEKYIAL YPNDTPSTDP 151 KGVELTNLRR EQFLKLVAER MDANTLNVSF EEILKGKKLD EDSIGLTLSP 201 DKDHEDGSQV SPTQDRKELD QVVGEDEKDD FFE*

Amino Acid Sequence (or in FASTA format)

       1  MAKLQRKRSK ALGSSLEMSQ IMDAGTNKIK RRIRDLERLL KKKKDILPST
      51  VIIEKERNLQ ALRLELQNNE LKNKIKANAK KYHMVRFFEK KKALRKYNRL
     101  LKKIKESGAD DKDLQQKLRA TKIELCYVIN FPKTEKYIAL YPNDTPSTDP
     151  KGVELTNLRR EQFLKLVAER MDANTLNVSF EEILKGKKLD EDSIGLTLSP
     201  DKDHEDGSQV SPTQDRKELD QVVGEDEKDD FFE*

external links for Efg1p

Homologs	Interaction Resources	Protein databases/Other	Localization Resources
BLASTP (NCBI)	BioGRID	SCOP Superfamily	YPL+
Ashbya (AGD)	BOND	GPMdb (Mass Spec.)	YeastGFP
Candida (CGD)	BioPIXIE	MIPS	YeastRC Public Image Repository
Candida (CandidaDB)	CYC2008 (complexes)
YGOB	Complexome
YOGY	GeneMANIA

References cited on this page View Complete Literature Guide for Efg1p

1)	Kastenmayer JP, et al. (2006) Functional genomics of genes with small open reading frames (sORFs) in S. cerevisiae. Genome Res 16(3):365-73
2)	Peng WT, et al. (2003) A panoramic view of yeast noncoding RNA processing. Cell 113(7):919-33
3)	Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4)	Ghaemmaghami S, et al. (2003) Global analysis of protein expression in yeast. Nature 425(6959):737-41