TFB5/YDR079C-A Protein Information Help

Standard Name Tfb5p 1
Systematic Name Ydr079c-ap
ORF Classification Verified
Description Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair (2, 3, 4)
Predicted Sequence Formatted Sequence or sequence in FASTA format
Length (a.a.) 72
Molecular Weight (Da) 8,232
Isoelectric Point (pI) 4.86

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Post-translational Modifications PhosphoGRID | PhosphoPep Database
Domains/motifs See the graphical view and list of proteins that share domains/motifs in common with Tfb5p (InterPro)
Physical Interactions There are 26 total physical interactions (BioGRID)
Homologs PDB Homologs | BLASTP | BLASTP v. fungi | Fungal Alignment | Synteny Viewer
External Sequence Databases EBI: UPI00001682E5 | Q3E7C1
MIPS: YDR079C-A
NCBI: 197107384 | 197107450 | 197107452 | 398365465 | 85541644 | NP_076886.3
GenBank/EMBL/DDBJ: DAA11926.1 | Z74376
Amino Acid Sequence (or in FASTA format)
       1  MARARKGALV QCDPSIKALI LQIDAKMSDI VLEELDDTHL LVNPSKVEFV
      51  KHELNRLLSK NIYNPMDEEE NQ*                             

external links for Tfb5p
Homologs Interaction Resources Protein databases/Other Localization Resources
BLASTP (NCBI) BioGRID SCOP Superfamily YPL+
Ashbya (AGD) BOND GPMdb (Mass Spec.) YeastGFP
Aspergillus (AspGD) BioPIXIE MIPS YeastRC Public Image Repository
Candida (CGD) CYC2008 (complexes) Pfam domains
Candida (CandidaDB) Complexome YeastRC Structure Prediction (Seattle)
YGOB DIP

YOGY GeneMANIA

References cited on this page View Complete Literature Guide for Tfb5p
1) Ranish. J.A. et al.  (2004) Quantitative proteomic identification of TFB5, a new component of general transcription/DNA repair factor IIH Nature Genetics
2) Ranish JA, et al.  (2004) Identification of TFB5, a new component of general transcription and DNA repair factor IIH. Nat Genet 36(7):707-13
3) Zhou Y, et al.  (2007) Tfb5 interacts with Tfb2 and facilitates nucleotide excision repair in yeast. Nucleic Acids Res 35(3):861-71
4) Ding B, et al.  (2007) Tfb5 is partially dispensable for Rad26 mediated transcription coupled nucleotide excision repair in yeast. DNA Repair (Amst) 6(11):1661-9